Nanjing, the host city of the 21st APEC SME Ministerial Meeting, has been leading various efforts to empower SMEs innovative and sustainable growth. One of their main strategies was to set up Nanjing SME IT Adoption Service Center. Through the evolvement of the organization and its activities in the last several years, they have accumulated successful experiences on how to promote the use of ICT among SMEs and on how to improve the level of ICT adoption in manufacture-on-demand, e-commerce application, logistics and supply chain collaboration, business management and others.